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February 1, 1992HypertensionOpen Access

Proceedings of the Ninth Scientific Meeting of the Inter-American Society of Hypertension. Rio de Janeiro, Brazil, March 10-13, 1991.

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Implication

Remodeling sustains hypertension via vasoconstrictor amplification; leaves open whether reversing media/lumen changes improves outcomes.

Key Points

  • This review aims to elucidate the structural and functional changes in small blood vessels that contribute to elevated blood pressure.
  • Assessment of mesenteric small arteries in hypertensive rats and humans to identify morphological changes.
  • Comparison of vasoconstriction responses in hypertensive and normotensive conditions.
  • Analysis of the interaction between structural alterations and blood pressure regulation.
  • Hypertensive rats showed significantly reduced lumen diameter and thickened vascular walls, affecting peripheral resistance.
  • Small resistance arteries from hypertensive humans exhibited similar structural alterations.
  • Overall, changes in blood vessel structure lead to increased vascular resistance, influencing hypertension development.

Cite This Study

A 1992 study studied this question.

synapsesocial.com/papers/6a6f9bd85d37378ac1dcab38https://doi.org/10.1161/01.hyp.19.2_suppl.ii1

Topics

Hypertension management
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