Why the study?
Does a high salt diet alter skeletal muscle microvasculature in Dahl salt-sensitive rats?
Population
Anesthetized Dahl salt-sensitive rats and age-matched Dahl salt-resistant rats
Comparison
High salt diet (7% sodium chloride) for 4 weeks vs Low-normal salt diet for 4 weeks
Design
Preclinical
Follow-up
4 weeks
Authors
Loading...
May support microvascular mechanism in experimental salt-sensitive hypertension; leaves open human relevance and therapeutic implications.
Does a high salt diet alter skeletal muscle microvasculature in Dahl salt-sensitive rats?
A high salt diet reduces the resting diameter of arcade arterioles in salt-sensitive rats, suggesting a mechanism for increased peripheral vascular resistance in salt-induced hypertension.
Boegehold et al. (1990) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: