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June 1, 2023Journal of Medical VirologyOpen Access

Predominance of DS‐1‐like G8P8 rotavirus reassortant strains in children hospitalized with acute gastroenteritis in Thailand, 2018–2020

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Why the study?

Rotavirus A is an important cause of acute gastroenteritis in children, motivating investigation into its molecular epidemiology in hospitalized pediatric patients.

Population

302 samples from children hospitalized with acute gastroenteritis in Chiang Rai, Thailand

Design

Molecular epidemiological study

Authors

WCWisoot Chan‐ItPibulsongkram Rajabhat UniversityCCChulapong ChantaChiangRai Prachanukroh HospitalHUHiroshi UshijimaNihon University

Discussion

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Overview

Highlights need for continued RVA surveillance in Thailand; leaves open vaccine effectiveness against dominant G8P[8].

Structured PICO

P
Population
302 samples from children hospitalized with acute gastroenteritis in Chiang Rai, Thailand in 2018-2020
O
Outcome
Detection and molecular epidemiology/genotyping of Rotavirus A

The study identifies a novel DS-1-like G8P[8] rotavirus reassortant strain as the predominant cause of acute gastroenteritis in hospitalized children in Chiang Rai, Thailand, between 2018 and 2020.

Cite This Study

Chan‐It et al. (2023) studied this question.

synapsesocial.com/papers/6a6faeeda528af2d65c31d05https://doi.org/10.1002/jmv.28870
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Development of RT-multiplex PCR Assay for Detection of Adenovirus and Group A and C Rotaviruses in Diarrheal Fecal Specimens from Children in China2004 · 108 citations
  2. 2Full Genome Characterization of Novel DS-1-Like G8P[8] Rotavirus Strains that Have Emerged in Thailand: Reassortment of Bovine and Human Rotavirus Gene Segments in Emerging DS-1-Like Intergenogroup Reassortant Strains2016 · 53 citations
  3. 3Predominant prevalence of human rotaviruses with the G1P[8] and G8P[8] genotypes with a short RNA profile in 2013 and 2014 in Sukhothai and Phetchaboon provinces, Thailand2016 · 28 citations
  4. 4Global, Regional, and National Estimates of Rotavirus Mortality in Children <5 Years of Age, 2000–20132016 · 1,076 citations
  5. 5Genomic Constellation of Human Rotavirus G8 Strains in Brazil over a 13-Year Period: Detection of the Novel Bovine-like G8P[8] Strains with the DS-1-like Backbone2023 · 13 citations