Population
Humans with essential hypertension and rat models of genetic hypertension
Design
Review
Authors
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Gene therapy for hypertension remains investigational; leaves open clinical translation of QTL mapping and gene transfer strategies from preclinical models.
This review highlights the progress and future directions in identifying genetic determinants of hypertension using animal models and genetic profiling to develop targeted gene therapies.
Dominiczak et al. (2000) studied this question.
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