Population
Human astrovirus isolate Yuc-8 from Mexico, adapted to grow in CaCo-2 cells
Comparison
Whole genome sequencing and comparative sequence… vs Reported human astrovirus sequences
Design
Preclinical
Authors
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Hypothesis-generating for astrovirus evolution; leaves open clinical relevance of genotype 8 features in humans.
Molecular analysis of the Yuc-8 human astrovirus isolate reveals it belongs to serotype 8 and suggests differential selective pressure on its structural polyprotein domains.
Méndez-Toss et al. (2000) studied this question.
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