Why the study?
Does nebivolol improve RDW and N/L ratio compared to metoprolol in patients with newly diagnosed essential hypertension?
Population
72 patients with newly diagnosed essential hypertension (38 men)
Comparison
Nebivolol 5 mg/d for 6 months vs Metoprolol 100 mg/d for 6 months
Design
RCT, randomly allocated
Follow-up
6 months
Authors
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Nebivolol may confer anti-inflammatory advantages over metoprolol in hypertension; extends beta-blocker pleiotropy data but requires outcome trials.
Does nebivolol improve RDW and N/L ratio compared to metoprolol in patients with newly diagnosed essential hypertension?
Nebivolol, but not metoprolol, significantly reduces RDW and N/L ratio in patients with newly diagnosed essential hypertension, suggesting potential anti-inflammatory benefits beyond blood pressure lowering.
Fıcı et al. (2013) studied this question.
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