Why the study?
Does nebivolol improve lipid profile and blood pressure compared to metoprolol in newly diagnosed patients with essential hypertension?
Population
60 newly diagnosed patients of essential hypertension with deranged lipid parameters according to National…
Comparison
Nebivolol 5 mg oral once daily for 12 weeks vs Metoprolol 50 mg oral once daily for 12 weeks
Design
RCT, Randomly allocated using random number table into two groups, Open label
Follow-up
12 weeks
Authors
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Favors nebivolol over metoprolol when lipids are a concern; extends RCT evidence for metabolic differences among beta-blockers.
Does nebivolol improve lipid profile and blood pressure compared to metoprolol in newly diagnosed patients with essential hypertension?
Nebivolol provides comparable blood pressure reduction to metoprolol but offers a significantly more favorable effect on the lipid profile in patients with essential hypertension.
Johar et al. (2015) studied this question.
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