Why the study?
Does nebivolol 5 mg daily improve lipid and carbohydrate metabolism and blood pressure compared to atenolol 50 mg daily in normometabolic patients with mild-to-moderate hypertension?
Population
Normometabolic subjects with mild-to-moderate essential hypertension
Comparison
Nebivolol 5 mg oral daily for 12 weeks vs Atenolol 50 mg oral daily for 12 weeks
Design
RCT, randomized, parallel study, double-blind
Follow-up
12 weeks
Authors
Loading...
Both agents provide equivalent BP control without metabolic disruption; confirms beta-blocker neutrality in normometabolic hypertension.
Does nebivolol 5 mg daily improve lipid and carbohydrate metabolism and blood pressure compared to atenolol 50 mg daily in normometabolic patients with mild-to-moderate hypertension?
Nebivolol and atenolol provide similar antihypertensive efficacy without adversely affecting lipid or carbohydrate metabolism in normometabolic hypertensive patients.
Pesant et al. (1999) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: