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October 1, 1993Japanese Journal of Clinical Oncology

Anastomotic Leakage after Colorectal Cancer Surgery: A Risk Factor for Recurrence and Poor Prognosis

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Why the study?

Does anastomotic leakage after colorectal cancer surgery increase the risk of local recurrence and poor prognosis?

Population

980 colorectal cancer patients who underwent anastomosis at Keio University Hospital between 1970 and 1990

Comparison

Anastomotic leakage (n=33) vs No anastomotic leakage

Design

Cohort

Authors

SFShin FujitaTochigi Cancer CenterTTTatsuo TeramotoChiba HospitalMWMasahiko WatanabeThe Japanese Society of Gastroenterological Surgery

Discussion

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Member takes

Overview

Anastomotic leakage may raise local recurrence risk after colorectal cancer surgery; leaves open causality and impact on early-stage management.

Structured PICO

Does anastomotic leakage after colorectal cancer surgery increase the risk of local recurrence and poor prognosis?

P
Population
980 colorectal cancer patients who underwent anastomosis at Keio University Hospital between 1970 and 1990
I
Intervention
Anastomotic leakage (n=33)
C
Comparator
No anastomotic leakage
O
Outcome
Incidence of local recurrence and disease-free survival ratehard clinical

Anastomotic leakage after colorectal cancer surgery is associated with a higher incidence of local recurrence and poorer disease-free survival in early-stage patients.

Cite This Study

Fujita et al. (1993) studied this question.

synapsesocial.com/papers/6a6fc344febe604dd7089d80https://doi.org/10.1093/oxfordjournals.jjco.a039651
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Prognosis After Anastomotic Leakage in Colorectal Surgery2005 · 471 citations
  2. 2Anastomotic Leakage Is Predictive of Diminished Survival After Potentially Curative Resection for Colorectal Cancer2004 · 462 citations
  3. 3The impact of anastomotic leakage on oncologic outcomes and the receipt and timing of adjuvant chemotherapy after colorectal cancer surgery2015 · 54 citations
  4. 4Influence of Anastomotic Leak After Elective Colorectal Cancer Resection on Survival and Local Recurrence: A Propensity Score Analysis2018 · 43 citations
  5. 5Clinical Burden of Anastomotic Leak After Elective Colorectal Cancer Surgery: A Multicenter Cohort Study2026