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August 14, 2015International Journal of SurgeryOpen Access

The impact of anastomotic leakage on oncologic outcomes and the receipt and timing of adjuvant chemotherapy after colorectal cancer surgery

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Why the study?

Does anastomotic leakage worsen oncologic outcomes and affect the receipt of adjuvant chemotherapy in patients undergoing major resection for colorectal cancer?

Population

809 consecutive patients undergoing major resection for colorectal cancer

Comparison

Anastomotic leakage vs No anastomotic leakage

Design

Cohort

Follow-up

5 years

Authors

IKIk Yong KimYonsei UniversityBKBo Ra KimDaewoo Electronics (South Korea)YKYoung Wan KimYonsei University

Discussion

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Implication

May warrant closer surveillance after anastomotic leak in stage II colorectal cancer; hypothesis-generating for effects on adjuvant chemotherapy timing.

Structured PICO

Does anastomotic leakage worsen oncologic outcomes and affect the receipt of adjuvant chemotherapy in patients undergoing major resection for colorectal cancer?

P
Population
809 consecutive patients undergoing major resection for colorectal cancer
I
Intervention
Anastomotic leakage
C
Comparator
No anastomotic leakage
O
Outcome
Oncologic outcomes (5-year local recurrence rates) and receipt/timing of adjuvant chemotherapyhard clinical

Anastomotic leakage after colorectal cancer surgery is associated with significantly higher local recurrence rates and decreased receipt of adjuvant chemotherapy.

Cite This Study

Kim et al. (2015) studied this question.

synapsesocial.com/papers/6a714dca75498292b70ac921https://doi.org/10.1016/j.ijsu.2015.08.017
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