January 1, 1995Clinical and Experimental Hypertension

Use of C-Fos Functional Mapping to Identify the Central Baroreceptor Reflex Pathway: Advantages and Limitations

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Population

Conscious and anaesthetized animals

Design

Review

Authors

RDR.A.L. DampneyGeneral Cardiology YLY.-W. LiThe University of Sydney YHYoshitaka HirookaGeneral Cardiology

Discussion

Member takes

Implication

Anesthetic confounds require controls in c-fos cardiovascular studies; leaves open standardized conscious-animal protocols for reflex mapping.

Structured PICO

Population

Conscious and anaesthetized animals

Intervention

c-fos functional mapping to identify central neurons involved in the baroreceptor reflex

Outcome

c-fos expression and identification of central neurons

C-fos functional mapping is a valuable tool for identifying central cardiovascular reflex pathways in conscious animals, but researchers must account for the confounding effects of different anaesthetic agents.

Cite This Study

Dampney et al. (1995) studied this question.

synapsesocial.com/papers/6a6fc640f44fa9f079dd43dd https://doi.org/10.3109/10641969509087065

Topics

Hypertension management

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Implication

Anesthetic confounds require controls in c-fos cardiovascular studies; leaves open standardized conscious-animal protocols for reflex mapping.

Use of C-Fos Functional Mapping to Identify the Central Baroreceptor Reflex Pathway: Advantages and Limitations

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Topics

Use of C-Fos Functional Mapping to Identify the Central Baroreceptor Reflex Pathway: Advantages and Limitations

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Topics

Also Consider