April 1, 1988Journal of VirologyOpen Access

Purification and partial characterization of poliovirus protease 2A by means of a functional assay

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Population

Poliovirus-infected cells

Design

Preclinical

Authors

Discussion

Enables biochemical characterization of poliovirus 2A; leaves open therapeutic targeting in this animal model.

Population

Poliovirus-infected cells

Intervention

Purification procedure involving detergent treatment, high-speed centrifugation, and gel filtration through Superose 12

Outcome

Purification and characterization of poliovirus protease 2Asurrogate

This study describes a rapid and efficient method for purifying poliovirus protease 2A, enabling its biochemical characterization.

König et al. (1988) studied this question.

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