Why the study?
Does severely impaired renal function affect heparin elimination in patients on haemodialysis?
Population
17 subjects including normal individuals, nephrectomized patients, and other uraemic patients on haemodialysis
Comparison
Heparin 100 U/kg bodyweight administered as a… vs Normal group
Design
Cohort
Authors
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May warrant heparin dose caution in nephrectomized patients; leaves open effects on bleeding risk during haemodialysis.
Does severely impaired renal function affect heparin elimination in patients on haemodialysis?
Severely impaired renal function has a significant but moderate influence on prolonging heparin elimination half-life.
Teien et al. (1976) studied this question.
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