Why the study?
Are renin-angiotensin system gene polymorphisms associated with cerebrovascular and cardiovascular diseases in dialysis patients?
Are renin-angiotensin system gene polymorphisms associated with cerebrovascular and cardiovascular diseases in dialysis patients?
The ACE gene D allele is associated with an increased risk of cerebrovascular disease and greater severity of carotid artery stenosis in patients on dialysis.
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ACE D allele may flag higher cerebrovascular risk in dialysis; leaves open whether genotyping guides prevention or trials.
Attilio Losito (2002) studied this question.
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