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February 1, 1991BJOG An International Journal of Obstetrics & Gynaecology

Angiotensin II levels in hypertensive and normotensive pregnancies

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Why the study?

Are circulating angiotensin II levels altered in women with pregnancy-induced hypertension compared to normal pregnancies?

Population

92 women, including women with pregnancy-induced hypertension, women with normal pregnancy, and non-pregnant…

Design

Cross-sectional

Authors

MHMyriam HanssensLeiden UniversityMKMarc J. N. C. KeirseLeiden UniversityBSBernard SpitzKU Leuven

Discussion

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Overview

Should not yet alter management of pregnancy-induced hypertension; leaves open mechanistic role of reduced angiotensin II in this cross-sectional association.

Structured PICO

Are circulating angiotensin II levels altered in women with pregnancy-induced hypertension compared to normal pregnancies?

P
Population
92 women, including women with pregnancy-induced hypertension (n=54), women with normal pregnancy (n=18), and non-pregnant women (n=20).
O
Outcome
Circulating angiotensin II levels measured by radioimmunoassaysurrogate

Women with pregnancy-induced hypertension have significantly lower circulating angiotensin II levels compared to those with normal pregnancies, resembling levels in non-pregnant women.

Cite This Study

Hanssens et al. (1991) studied this question.

synapsesocial.com/papers/6a6ff536febe604dd708c5ddhttps://doi.org/10.1111/j.1471-0528.1991.tb13361.x

Topics

Hypertension management
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Plasma Renin Activity, Plasma Angiotensin and Plasma and Urinary Electrolytes in Normal and Toxaemic Pregnancy, Including a Prospective Study1973 · 69 citations
  2. 2Immunoreactive Renin, Prorenin, and Enzymatically Active Renin in Plasma during Pregnancy and in Women Taking Oral Contraceptives*1986 · 147 citations
  3. 3Hypertension in Pregnancy1981 · 383 citations
  4. 4Hypertensive Disorders in Pregnancy1978 · 274 citations