Why the study?
Does nifedipine improve left ventricular function and reduce hypertrophy in patients with hypertensive heart disease, hypertrophic non-obstructive cardiomyopathy, coronary artery disease, and dilatative cardiomyopathy?
Population
Patients with hypertensive and normotensive hypertrophy and advanced cardiac disease due to coronary artery…
Design
Cohort
Follow-up
mean 3.9 months
Authors
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Nifedipine was associated with LV function gains and hypertrophy regression in hypertrophic non-obstructive cardiomyopathy; hypothesis-generating and requires randomized confirmation before practice change.
Does nifedipine improve left ventricular function and reduce hypertrophy in patients with hypertensive heart disease, hypertrophic non-obstructive cardiomyopathy, coronary artery disease, and dilatative cardiomyopathy?
Long-term high-dose nifedipine therapy improves left ventricular function and induces regression of left ventricular hypertrophy in patients with hypertensive heart disease and hypertrophic non-obstructive cardiomyopathy.
Strauer et al. (1984) studied this question.
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