Key result
Long-term nifedipine monotherapy significantly reduced left ventricular mass by a mean of 15% in patients with systemic hypertension.
Why the study?
Does nifedipine monotherapy reduce left ventricular hypertrophy in patients with systemic hypertension?
Population
9 patients with systemic hypertension and left ventricular (LV) hypertrophy.
Design
Case_series
Follow-up
mean 50 months (13-105 months)
Authors
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Hypothesis-generating for nifedipine in hypertensive LVH; leaves open confirmation in randomized trials.
Observational (n=9)
Does nifedipine monotherapy reduce left ventricular hypertrophy in patients with systemic hypertension?
Long-term nifedipine monotherapy significantly reduces blood pressure and reverses left ventricular hypertrophy in patients with systemic hypertension.
Yamakado et al. (1994) conducted an observational in Systemic hypertension (n=9). Nifedipine vs. Baseline was evaluated on Left ventricular mass. Long-term nifedipine monotherapy significantly reduced left ventricular mass by a mean of 15% in patients with systemic hypertension.