Why the study?
Increased cf-PWV in ESRD indicates enhanced aortic stiffness and mortality risk, leading researchers to evaluate the effects of nonpharmacologic interventions on cf-PWV, SBP, and adverse events.
Do nonpharmacologic interventions reduce carotid-femoral pulse wave velocity and systolic blood pressure in adults with end-stage renal disease?
Population
Adults with ESRD
Comparison
Nonpharmacologic interventions vs comparator
Design
Systematic review and meta-analysis
Authors
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Kidney transplant and low-calcium dialysate reduce cf-PWV in ESRD; extends support for targeted nonpharmacologic strategies to lower CV risk.
Do nonpharmacologic interventions reduce carotid-femoral pulse wave velocity and systolic blood pressure in adults with end-stage renal disease?
Nonpharmacologic interventions effectively decrease aortic stiffness in end-stage renal disease, though their impact on hard cardiovascular outcomes remains to be determined.
Rodriguez et al. (2019) studied this question.
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