Population
Isolated guinea pig ventricular myocytes
Comparison
Substitution of external solution containing 140… vs External solution containing 140 mM NaCl
Design
Preclinical
Authors
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May warrant caution with iodide exposure in cardiac patients; leaves open translation to human electrophysiology.
Sodium iodide specifically attenuates cAMP-dependent protein kinase-mediated regulation of cardiac calcium and chloride currents in guinea pig ventricular myocytes.
Walsh et al. (1992) studied this question.
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