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December 1, 2009Clinical CardiologyOpen Access

Intrasubject variability of RHI (CV) was 15.3% +/- 5.3%, 16.1%+/- 7.8%, and 22.6% +/- 3.9% for tests at 0.5, 1, and 2 hour intervals, respectively, with interday reproducibility (ICC) ranging from -0.07 to 0.47.

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Why the study?

What is the intrasubject variability and interday reproducibility of reactive hyperemia index (RHI) measured by repetitive peripheral arterial tonometry (PAT) in healthy men?

Population

22 healthy male subjects

Design

Cohort

Follow-up

3 consecutive days

Authors

JLJianmin LiuJWJingzhu WangYJYan Jin

Discussion

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Overview

RHI variability cautions against serial clinical monitoring; leaves open protocol optimization for research use.

Structured PICO

What is the intrasubject variability and interday reproducibility of reactive hyperemia index (RHI) measured by repetitive peripheral arterial tonometry (PAT) in healthy men?

P
Population
22 healthy male subjects
I
Intervention
Repetitive peripheral arterial tonometry (PAT) measurements at 0.5 hour, 1 hour, and 2 hour intervals
O
Outcome
Variability of the reactive hyperemia index (RHI) including intrasubject variability (CV) and interday reproducibility (ICC)surrogate

Repetitive PAT measurements show no carryover effect at 1- and 2-hour intervals, but interday reproducibility is relatively low, comparable to brachial artery ultrasound.

Cite This Study

Liu et al. (2009) studied this question.

synapsesocial.com/papers/6a700ccbfe4101aa97dffd5dhttps://doi.org/10.1002/clc.20668
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