Why the study?
Does the timing of Endo-PAT measurements affect the repeatability of Reactive Hyperemia Index (RHI) in healthy volunteers?
Population
Healthy volunteers (31 male subjects for interday repeatability, 16 volunteers for intraday repeatability)
Design
Cross-sectional
Follow-up
Up to 2 consecutive days
Key result
Multiple Endo-PAT measurements within the same day significantly increased the reactive hyperemia index by 30.1% at 4 hours compared to baseline, demonstrating poor intraday repeatability.
Authors
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May caution against repeated same-day Endo-PAT testing; supports protocol standardization in microvascular research.
Observational (n=47)
No
Does the timing of Endo-PAT measurements affect the repeatability of Reactive Hyperemia Index (RHI) in healthy volunteers?
p-value: p=<0.001
Endo-PAT measurements of RHI show good interday but poor intraday repeatability, highlighting the need to standardize protocols and avoid multiple same-day measurements.
Bo’ et al. (2016) conducted an observational in Healthy (n=47). Multiple intraday Endo-PAT measurements vs. Baseline measurement was evaluated on Intraday repeatability of reactive hyperemia index (RHI) (p=<0.001). Multiple Endo-PAT measurements within the same day significantly increased the reactive hyperemia index by 30.1% at 4 hours compared to baseline, demonstrating poor intraday repeatability.