May 3, 2017Frontiers in NeurologyOpen Access

Repeated measurements of fRHI showed moderate reliability on same-day and substantial reliability on day-to-day measurements, with day-to-day correlation being far better than same-day measurements.

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Why the study?

Does repeated endothelial function measurement using EndoPAT show reliability in acute stroke patients and healthy subjects?

Population

41 subjects total: 20 healthy volunteers and 21 acute stroke patients.

Design

Cross-sectional

Follow-up

24 hours

Authors

AHAina S. HansenGentofte Hospital JBJawad H. ButtHeart Failure / Cardiomyopathy SHSonja Holm‐YildizUniversity of Copenhagen

Discussion

Member takes

Overview

fRHI shows moderate same-day and substantial day-to-day reliability in acute stroke; leaves open its role in personalized prevention trials.

Structured PICO

Does repeated endothelial function measurement using EndoPAT show reliability in acute stroke patients and healthy subjects?

Population

41 subjects total: 20 healthy volunteers (men 50%, mean age 35.85 ± 3.47 years) and 21 acute stroke patients (men 52%, mean age 66.38 ± 2.85 years, mean NIHSS 4.09 ± 0.53).

Intervention

Repeated endothelial function measurements using EndoPAT2000 separated by 1.5 hours and 24 hours.

Outcome

Reliability of repeated endothelial function measurements (reactive hyperemia index [RHI], logarithm of RHI [lnRHI], and Framingham RHI [fRHI]) at 1.5 and 24 hours.surrogate

Repeated endothelial function measurements using EndoPAT show better day-to-day than same-day reliability, suggesting a potential carryover effect that should be considered in future studies.

Cite This Study

Hansen et al. (2017) studied this question.

synapsesocial.com/papers/6a700cc6fe4101aa97dffd5c https://doi.org/10.3389/fneur.2017.00178

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May 3, 2017Frontiers in NeurologyOpen Access

Repeated measurements of fRHI showed moderate reliability on same-day and substantial reliability on day-to-day measurements, with day-to-day correlation being far better than same-day measurements.

View Full Paper

Ask AI

Bookmark

Why the study?

Does repeated endothelial function measurement using EndoPAT show reliability in acute stroke patients and healthy subjects?

Population

41 subjects total: 20 healthy volunteers and 21 acute stroke patients.

Design

Cross-sectional

Follow-up

24 hours

Authors

AHAina S. HansenGentofte Hospital JBJawad H. ButtHeart Failure / Cardiomyopathy SHSonja Holm‐YildizUniversity of Copenhagen

Discussion

Member takes

Overview

fRHI shows moderate same-day and substantial day-to-day reliability in acute stroke; leaves open its role in personalized prevention trials.

Structured PICO

Does repeated endothelial function measurement using EndoPAT show reliability in acute stroke patients and healthy subjects?

Population

41 subjects total: 20 healthy volunteers (men 50%, mean age 35.85 ± 3.47 years) and 21 acute stroke patients (men 52%, mean age 66.38 ± 2.85 years, mean NIHSS 4.09 ± 0.53).

Intervention

Repeated endothelial function measurements using EndoPAT2000 separated by 1.5 hours and 24 hours.

Outcome

Reliability of repeated endothelial function measurements (reactive hyperemia index [RHI], logarithm of RHI [lnRHI], and Framingham RHI [fRHI]) at 1.5 and 24 hours.surrogate

Repeated endothelial function measurements using EndoPAT show better day-to-day than same-day reliability, suggesting a potential carryover effect that should be considered in future studies.

Cite This Study

Hansen et al. (2017) studied this question.

synapsesocial.com/papers/6a700cc6fe4101aa97dffd5c https://doi.org/10.3389/fneur.2017.00178

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

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