December 29, 2014PLoS ONEOpen Access

Cardiac Mechanics and Ventricular Twist by Three-Dimensional Strain Analysis in Relation to B-Type Natriuretic Peptide as a Clinical Prognosticator for Heart Failure Patients

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Why the study?

Does 3D-based myocardial deformation and twist analysis predict cardiovascular death or heart failure hospitalization in patients with hypertension or heart failure?

Population

200 subjects with known hypertension, diastolic heart failure, or systolic heart failure, recruited from…

Design

Cohort

Follow-up

mean 567.7 days (25th-75th IQR: 197-909 days)

Authors

SCSheng‐Nan ChangNational Taiwan University Hospital YLYau‐Huei LaiMackay Memorial Hospital CYChih‐Hsuan YenNational Taipei University of Technology

Discussion

Member takes

Implication

3D strain may refine risk stratification beyond LVEF in hypertension or HF; leaves open prospective validation before clinical adoption.

Structured PICO

Does 3D-based myocardial deformation and twist analysis predict cardiovascular death or heart failure hospitalization in patients with hypertension or heart failure?

Population

200 subjects (mean age: 60.2±16 years, 54% female) with known hypertension (n=51), diastolic heart failure (n=61), or systolic heart failure (n=30), recruited from heart failure outpatient clinics, and 58 healthy volunteers as a control group.

Intervention

3D-based myocardial deformation and twist analysis (3D echocardiography)

Outcome

Composite of cardiovascular related death or hospitalization due to heart failurecomposite

3D-based strain analysis provides prognostic value beyond traditional ejection fraction for predicting cardiovascular death or heart failure hospitalization.

Cite This Study

Chang et al. (2014) studied this question.

synapsesocial.com/papers/6a7010b3f44fa9f079dd96a1 https://doi.org/10.1371/journal.pone.0115260

Topics

Heart failure HFrEF treatment Hypertension management

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Cardiac Mechanics and Ventricular Twist by Three-Dimensional Strain Analysis in Relation to B-Type Natriuretic Peptide as a Clinical Prognosticator for Heart Failure Patients

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Topics

Cardiac Mechanics and Ventricular Twist by Three-Dimensional Strain Analysis in Relation to B-Type Natriuretic Peptide as a Clinical Prognosticator for Heart Failure Patients

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Topics

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