Why the study?
Does exogenous glucocorticoid treatment alter circadian blood pressure variations in patients with CGN and SLE?
Population
Patients with essential hypertension, chronic glomerulonephritis, and systemic lupus erythematosus…
Comparison
Prednisolone or other exogenous glucocorticoids vs Patients not receiving glucocorticoids, or…
Design
Cohort
Follow-up
mean 58.0 +/- 19.4 days
Authors
Loading...
Glucocorticoid use may blunt nocturnal BP dipping in CGN/SLE; leaves open HPA axis role in circadian BP regulation.
Does exogenous glucocorticoid treatment alter circadian blood pressure variations in patients with CGN and SLE?
Exogenous glucocorticoid treatment abolishes the normal nocturnal fall in blood pressure, suggesting the hypothalamo-pituitary-adrenal axis influences circadian blood pressure variation.
Imai et al. (1989) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: