What question did this study set out to answer?

To evaluate the impact of continuous 24-hour blood pressure levels during the first day of acute stroke on short-term functional recovery and long-term mortality in elderly patients.

July 19, 2013StrokeOpen Access

Systolic Blood Pressure During Acute Stroke Is Associated With Functional Status and Long-term Mortality in the Elderly

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Why the study?

Is high systolic blood pressure during the first day of acute stroke associated with worse short-term functional status and long-term mortality in elderly patients?

Population

177 elderly patients with acute stroke, mean age 84±6 years, 89 men.

Design

Cohort

Follow-up

up to 5 years (mean 2.07±1.48 years)

Authors

AWAvraham WeissRabin Medical Center YBYichayaou BelooseskyRabin Medical Center RKRon S. KenettSamuel Neaman Institute for National Policy Research

Discussion

Member takes

Implication

Should not yet change acute BP targets in stroke; extends observational data but leaves causal effects and interventions open.

Key Points

To evaluate the impact of continuous 24-hour blood pressure levels during the first day of acute stroke on short-term functional recovery and long-term mortality in elderly patients.
Prospective cohort study of 177 acute stroke patients (89 men, mean age 84±6 years) undergoing 24-hour blood pressure monitoring within 24 hours of hospital admission.
Assessed functional outcomes at 7 days using the modified Rankin Scale and tracked all-cause mortality over a follow-up of up to 5 years (mean 2.07±1.48 years).
Over the follow-up period, 71 patients died, with mortality significantly higher in women than in men (50% vs. 30%, P<0.01) and among patients with a history of congestive heart failure.
Average systolic blood pressure from 24-hour monitoring was the only hemodynamic factor predicting short-term functional status and long-term mortality.
Cox proportional hazards modeling demonstrated that average systolic blood pressure >160 mm Hg, older age, female sex, and congestive heart failure were independently associated with increased mortality.

Structured PICO

Is high systolic blood pressure during the first day of acute stroke associated with worse short-term functional status and long-term mortality in elderly patients?

Population

177 elderly patients with acute stroke, mean age 84±6 years, 89 men.

Intervention

Average systolic blood pressure >160 mm Hg recorded by 24-hour blood pressure monitoring during the first day of stroke

Outcome

Short-term functional status (modified Rankin Scale at 7 days) and long-term mortality (up to 5 years)hard clinical

High systolic blood pressure (>160 mm Hg) during the first 24 hours of acute stroke predicts worse short-term functional outcomes and higher long-term mortality in elderly patients.

Cite This Study

Weiss et al. (2013) studied this question.

synapsesocial.com/papers/6a70201678a11c550e09f26e https://doi.org/10.1161/strokeaha.113.001894

Topics

Heart failure HFrEF treatment

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Systolic Blood Pressure During Acute Stroke Is Associated With Functional Status and Long-term Mortality in the Elderly

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Topics

Systolic Blood Pressure During Acute Stroke Is Associated With Functional Status and Long-term Mortality in the Elderly

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Also Consider

Topics

Also Consider