Why the study?
What patient characteristics determine the dose requirements for thiopental anesthetic induction?
What patient characteristics determine the dose requirements for thiopental anesthetic induction?
Thiopental induction dose requirements are strongly determined by a combination of age, weight/lean body mass, and cardiac output.
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Supports including cardiac output with age and weight in thiopental dosing models; hypothesis-generating pending prospective validation.
Avram et al. (1993) studied this question.
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