Why the study?
What are the renal effects and metabolism of isoflurane compared to halothane in surgical patients?
Population
15 surgical patients
Comparison
Isoflurane vs Halothane
Design
Cohort
Follow-up
6 hours
Authors
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Minimal isoflurane metabolism yields low fluoride levels; leaves open whether renal safety differs from halothane in surgical patients.
What are the renal effects and metabolism of isoflurane compared to halothane in surgical patients?
Isoflurane is metabolized to a slight extent in surgical patients, producing low levels of serum inorganic fluoride.
Mazze et al. (1974) studied this question.
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