Why the study?
Does enflurane anesthesia affect renal function compared to halothane in surgical patients without renal disease?
Population
20 surgical patients without renal disease
Comparison
Enflurane anesthesia vs Halothane anesthesia
Design
Cohort
Follow-up
postanesthetic period (at least 4 hours)
Authors
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Enflurane appears safe for renal function in patients with normal baseline; leaves open randomized comparisons with halothane.
Does enflurane anesthesia affect renal function compared to halothane in surgical patients without renal disease?
Enflurane anesthesia produces inorganic fluoride but does not cause clinically significant renal dysfunction in patients with normal baseline renal function.
Cousins et al. (1976) studied this question.
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