Why the study?
How does enflurane anaesthesia affect renal fluoride excretion and is it dependent on urinary pH?
Population
7 patients undergoing enflurane anaesthesia and surgery
Comparison
Enflurane anaesthesia vs Pre-operative baseline
Design
Cohort
Follow-up
Post-operative period (at least 2 hours)
Authors
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Fluoride clearance falls markedly during enflurane anaesthesia in a pH-dependent manner; leaves open whether urinary alkalinization alters fluoride retention or outcomes.
How does enflurane anaesthesia affect renal fluoride excretion and is it dependent on urinary pH?
Renal fluoride excretion during and after enflurane anaesthesia is highly dependent on spontaneous variations in urinary pH.
Järnberg et al. (1980) studied this question.
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