Why the study?
Does renal function affect fluoride ion kinetics after enflurane anesthesia?
Population
40 patients, including 16 healthy patients, 18 anephric patients, and 6 patients with creatinine clearance <…
Comparison
Enflurane anesthesia vs Comparison among healthy, anephric, and poor…
Design
Cohort
Follow-up
24 hours post-anesthesia
Authors
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Enflurane may be used across renal function levels without fluoride toxicity concern; extends observational kinetics data but leaves open need for prospective trials.
Does renal function affect fluoride ion kinetics after enflurane anesthesia?
Enflurane anesthesia does not lead to toxic inorganic fluoride levels even in anephric patients or those with severe renal impairment, as serum levels fall rapidly due to presumed bone uptake.
Carter et al. (1976) studied this question.
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