June 1, 1981Acta Anaesthesiologica Scandinavica

Metabolic Ability and Enflurane Defluorination in Surgical Patients

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Why the study?

Does enflurane anaesthesia dose correlate with serum fluoride concentrations and fluoride excretion in surgical patients?

Population

21 surgical patients (14 tested for metabolic ability prior to anaesthesia)

Design

Cohort

Follow-up

24 hours post-anaesthesia

Authors

PRPer H. RosenbergUniversity of Applied Sciences Wedel MOM. OikkonenHelsinki University Hospital PNPertti J. NeuvonenGeneral / Preventive / Lipids

Discussion

Member takes

Implication

Enflurane dose associated with higher fluoride; hypothesis-generating for urine output strategies but should not yet change practice.

Structured PICO

Does enflurane anaesthesia dose correlate with serum fluoride concentrations and fluoride excretion in surgical patients?

Population

21 surgical patients (14 tested for metabolic ability prior to anaesthesia)

Intervention

Enflurane anaesthesia (mean dose 0.4 end-tidal vol. % X h in the subgroup of 14)

Outcome

Serum fluoride concentrations and fluoride excretion in urinesurrogate

Enflurane dose correlates with serum fluoride levels and urinary excretion, suggesting that maintaining good urinary output and higher urine pH may prevent inorganic fluoride accumulation.

Cite This Study

Rosenberg et al. (1981) studied this question.

synapsesocial.com/papers/6a86ee4f36c36f97809ec3ce https://doi.org/10.1111/j.1399-6576.1981.tb01645.x

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Metabolic Ability and Enflurane Defluorination in Surgical Patients

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Metabolic Ability and Enflurane Defluorination in Surgical Patients

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider