January 1, 1995Anesthesia & Analgesia

Splanchnic and Renal Sympathetic Activity in Relation to Hemodynamics During Isoflurane Administration in Pigs

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Why the study?

Does isoflurane administration affect regional sympathetic activity and hemodynamics in chloralose-anesthetized swine?

Population

Chloralose-anesthetized swine

Comparison

Administration of 1.4% isoflurane vs Before administration of isoflurane (baseline)

Design

Preclinical

Authors

AÅAnders ÅnemanGeneral Cardiology JPJ. PonténHallands sjukhus Halmstad LFLars FändriksSahlgrenska University Hospital

Discussion

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Implication

Isoflurane may reduce porcine mesenteric and renal sympathetic outflow; leaves open human hemodynamic relevance.

Structured PICO

Does isoflurane administration affect regional sympathetic activity and hemodynamics in chloralose-anesthetized swine?

Population

Chloralose-anesthetized swine

Intervention

Administration of 1.4% isoflurane

Comparator

Before administration of isoflurane (baseline)

Outcome

Regional sympathetic activity (norepinephrine spillover) and hemodynamics (vascular resistance, blood flow)surrogate

Isoflurane administration in swine reduces mesenteric and renal sympathetic outflow, contributing to decreased vascular resistance in these regions.

Cite This Study

Åneman et al. (1995) studied this question.

synapsesocial.com/papers/6a70208035aa2c282ce16dff https://doi.org/10.1097/00000539-199501000-00023

View Full Paper

Ask AI

Bookmark

Splanchnic and Renal Sympathetic Activity in Relation to Hemodynamics During Isoflurane Administration in Pigs

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Splanchnic and Renal Sympathetic Activity in Relation to Hemodynamics During Isoflurane Administration in Pigs

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider