October 10, 2018European Heart Journal - Cardiovascular Imaging
Coexistent bicuspid aortic valve and mitral valve prolapse: epidemiology, phenotypic spectrum, and clinical implications
Population
130 subjects with coexistent mitral valve prolapse and bicuspid aortic valve, 81% men, mean age 51 ± 16…
Design
Cohort
Follow-up
median 5.5 months (4-83)
Authors
Discussion
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Overview
MVP-BAV coexistence may signal higher risk; hypothesis-generating for phenotype-specific prognosis pending prospective studies.
Structured PICO
P
Population
130 subjects with coexistent mitral valve prolapse (MVP) and bicuspid aortic valve (BAV), 81% men, mean age 51 ± 16 years old, evaluated between 2005 and 2015.
C
Comparator
Patients with MVP and tricuspid aortic valve (TAV), as well as internal comparisons between MVP-BAV phenotypes (e.g., GAP-BAV vs posterior-MVP-BAV).
O
Outcome
Prevalence, phenotypic expression, and clinical significance of coexistent MVP-BAV.
Coexistent MVP and BAV frequently presents with an anterior mitral leaflet prolapse phenotype, including an extreme variant (GAP-BAV) that is associated with high rates of mitral repair failure.
Cite This Study
Padang et al. (2018) studied this question.