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September 1, 1966Rubber Chemistry and Technology

Elastomers for Use in Heart Valves

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Population

Elastomeric materials for artificial heart valve prostheses, including silicone rubber balls from an…

Comparison

New elastomeric materials including butyl… vs Standard silicone rubber balls.

Design

Preclinical

Authors

DRD.A. RaibleUnited States Department of Veterans AffairsDKD. P. KellerWPWill R. PierieOregon Medical Research Center

Discussion

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Overview

Laboratory data position butyl rubber as candidate material for ball valves; leaves open in vivo durability and clinical translation.

Structured PICO

P
Population
Elastomeric materials for artificial heart valve prostheses, including silicone rubber balls from an estimated 18,000 implanted Starr-Edwards valves.
I
Intervention
New elastomeric materials including butyl, ethylene propylene, polybutadiene, and chlorohydrin rubbers.
C
Comparator
Standard silicone rubber balls (variant and non-variant).
O
Outcome
Physical properties, wear resistance, and resilience in laboratory durability testers.surrogate

Laboratory evaluation suggests that butyl rubber, which has low resilience, offers excellent wear resistance and may be advantageous for ball-type heart valve prostheses compared to standard silicone.

Cite This Study

Raible et al. (1966) studied this question.

synapsesocial.com/papers/6a702bb431a3df824328723fhttps://doi.org/10.5254/1.3547136
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Analyses of a silicone elastomer heart ball valve1973 · 6 citations
  2. 2A Novel Design and Simulation of a Nano Prosthetic Artificial Heart Valves2023
  3. 3A Mitral Heart Valve Prototype Using Sustainable Polyurethane Polymer: Fabricated by 3D Bioprinter, Tested by Molecular Dynamics Simulation2021 · 17 citations
  4. 4Surface ultrastructure of silicone rubber aortic valve poppetts after long-term implantation. A scanning electron microscope study of four poppets.1976 · 11 citations
  5. 5Radiographic Diagnosis of Aortic-Ball Variance1969 · 31 citations