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December 1, 1976ThoraxOpen Access

Surface ultrastructure of silicone rubber aortic valve poppetts after long-term implantation. A scanning electron microscope study of four poppets.

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Key result

Scanning electron microscopy of four implanted Silastic aortic valve poppets showed dense coating with biological debris, but the underlying Silastic surface was little altered even after 10 years.

Population

4 implanted Silastic aortic valve poppets from patients

Comparison

Scanning electron microscopy vs Unimplanted poppets

Design

Case_series

Follow-up

up to 10 years

Authors

SASally P. AllworkUniversity College LondonRNRaymond S. NortonAustralian Regenerative Medicine Institute

Discussion

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Member takes

Implication

Supports Silastic durability in long-term implants; leaves open clinical impact of debris coating.

Study Design

Type

Case Report (n=4)

Structured PICO

P
Population
4 implanted Silastic aortic valve poppets from patients (2 discovered at necropsy, 1 replaced clinically, 1 reoperation)
I
Intervention
Scanning electron microscopy
C
Comparator
Unimplanted poppets
O
Outcome
Surface ultrastructuresurrogate

Long-term implantation of Silastic aortic valve poppets results in a dense coating of biological debris and microthrombi, but the underlying silicone rubber surface remains largely unaltered.

Cite This Study

Allwork et al. (1976) conducted a case report in Implanted Silastic aortic valve poppets (n=4). Silastic aortic valve poppets vs. Unimplanted poppets was evaluated on Surface ultrastructure. Scanning electron microscopy of four implanted Silastic aortic valve poppets showed dense coating with biological debris, but the underlying Silastic surface was little altered even after 10 years.

synapsesocial.com/papers/6a08cba58bd2868868ba0661https://doi.org/10.1136/thx.31.6.742
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Death Due to Swelling of Ball Component of Aortic Ball-Valve Prosthesis1967 · 38 citations
  2. 2Erythrocyte Destruction in Different Types of Starr-Edwards Aortic Ball Valves1970 · 50 citations
  3. 3Death Due to Migration of the Ball From an Aortic-Valve Prosthesis1965 · 42 citations
  4. 4Intravascular Haemolysis, Platelet Consumption and Platelet Adhesiveness in Patients with Prosthetic Heart Valves1971 · 14 citations
  5. 5Five-Year Experience with Magovern Aortic Prostheses1971 · 11 citations