Key result
Solubility parameter theory predicts that highly polar compounds, such as phospholipids or proteins, should not be present in silicone rubber prosthetic heart valve poppets.
Population
Prosthetic heart valve poppets (silicone rubber and other commonly used materials)
Design
Other
Authors
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Theory supports silicone poppet resistance to polar uptake; leaves open in vivo durability testing before practice change.
Solubility parameter theory can be used to predict lipid uptake in prosthetic heart valve poppets, confirming that highly polar compounds do not accumulate in silicone rubber.
Moacanin et al. (1973) studied Prosthetic heart valve poppet deterioration. Solubility parameter theory analysis was evaluated on Prediction of lipid uptake in silicone rubber poppets. Solubility parameter theory predicts that highly polar compounds, such as phospholipids or proteins, should not be present in silicone rubber prosthetic heart valve poppets.