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January 1, 2001Echocardiography

Quantitative Assessment of Fetal Ventricular Function: Establishing Normal Values of the Myocardial Performance Index in the Fetus

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Why the study?

What are the normal values of the myocardial performance index (MPI) in fetuses, and how do they compare to normal children?

Population

125 normal fetuses and 152 normal children

Comparison

Measurement of right ventricular and left… vs Comparison between fetuses and normal children…

Design

Cross-sectional

Authors

BEBenjamin W. EidemMayo Clinic in ArizonaJEJeanette EdwardsManitoba HealthFCFrank CettaPediatric Cardiology

Discussion

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Implication

Supplies normative fetal MPI values for ventricular function assessment; extends pediatric norms but leaves open validation in disease states.

Structured PICO

What are the normal values of the myocardial performance index (MPI) in fetuses, and how do they compare to normal children?

P
Population
125 normal fetuses (20-40 weeks gestation, mean age 28 weeks) and 152 normal children (age 3-18 years, mean age 9.3 years)
I
Intervention
Measurement of right ventricular (RV) and left ventricular (LV) myocardial performance index (MPI) via Doppler echocardiography
C
Comparator
Comparison between fetuses and normal children, and across five fetal gestational age groups
O
Outcome
Right ventricular (RV) and left ventricular (LV) myocardial performance index (MPI) valuessurrogate

The myocardial performance index (MPI) is a feasible and reproducible Doppler echocardiographic measure of fetal ventricular function, with normal values similar to those in children and independent of gestational age.

Cite This Study

Eidem et al. (2001) studied this question.

synapsesocial.com/papers/6a702ea726a7f98052dcb058https://doi.org/10.1046/j.1540-8175.2001.t01-1-00009.x
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Fetal left ventricular myocardial performance index: Defining normal values for Indian population and a review of literature2016 · 19 citations
  2. 2Validation of the fetal myocardial performance index in the second and third trimesters of gestation2008 · 82 citations
  3. 3The (Pulsed-Wave) Doppler Fetal Myocardial Performance Index: Technical Challenges, Clinical Applications and Future Research2015 · 48 citations
  4. 4Fetal Cardiac Function: Myocardial Performance Index2021 · 25 citations
  5. 5Normal values fetal modified myocardial performance index in the russian population and association with gestational age2020 · 1 citations