Why the study?
Does increasing left heart filling pressure beyond 12 mm Hg improve cardiac performance in patients with hypovolemic and septic shock?
Population
15 patients undergoing fluid resuscitation for hypovolemic and septic shock
Comparison
Fluid resuscitation to increase pulmonary artery… vs Baseline and intermediate WP vs higher WP
Design
Case_series
Authors
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May support targeting WP ~12 mm Hg to optimize cardiac performance in shock; hypothesis-generating from single case report.
Does increasing left heart filling pressure beyond 12 mm Hg improve cardiac performance in patients with hypovolemic and septic shock?
In patients with hypovolemic and septic shock, fluid resuscitation to a wedge pressure of approximately 12 mm Hg optimizes cardiac performance, with no further hemodynamic benefit observed at higher filling pressures.
Packman et al. (1983) studied this question.
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