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August 1, 1999Acta Physiologica Scandinavica

Hyperoxia does not increase peak muscle oxygen uptake in small muscle group exercise

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Why the study?

Does inspiring 60% O2 increase peak muscle oxygen uptake in young trained individuals during small muscle group exercise?

Population

8 young, trained individuals (5 men, 3 women)

Comparison

Inspiring 60% O2 during single-leg… vs Inspiring normal air during the same exercise

Design

Other

Authors

PPPer Kent PedersenUniversity of CalgaryBKBente KiensUniversity of Copenhagen
Bengt Saltin
Bengt SaltinPreventive Cardiology

Discussion

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Overview

Hyperoxia does not raise limb VO2peak in small-muscle exercise; leaves open peripheral limitation to VO2peak in trained individuals.

Structured PICO

Does inspiring 60% O2 increase peak muscle oxygen uptake in young trained individuals during small muscle group exercise?

P
Population
8 young, trained individuals (5 men, 3 women)
I
Intervention
Inspiring 60% O2 (HiOX) during single-leg knee-extension exercise at 70% and 100% of maximum
C
Comparator
Inspiring normal air (NOX) during the same exercise
O
Outcome
Peak oxygen uptake (VO2peak) of the exercising limbsurrogate

Hyperoxia does not increase peak muscle oxygen uptake during small muscle group exercise, suggesting a peripheral limitation for VO2peak such as mitochondrial O2 turnover saturation or tissue diffusion limitation.

Cite This Study

Pedersen et al. (1999) studied this question.

synapsesocial.com/papers/6a70464bac440176ef28ed0dhttps://doi.org/10.1046/j.1365-201x.1999.00575.x
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Effect of changes in arterial oxygen content on circulation and physical performance1975 · 175 citations
  2. 2Non‐linear relationship between O2 uptake and power output at high intensities of exercise in humans.1995 · 174 citations
  3. 3Muscular Exercise, Lactic Acid, and the Supply and Utilization of Oxygen1923 · 1,003 citations
  4. 4Chemical energetics of slow- and fast-twitch muscles of the mouse.1982 · 556 citations
  5. 5A Longitudinal Study of Adaptive Changes in Oxygen Transport and Body Composition1968 · 183 citations