Population
Rats and primary cultures of rabbit cortical thick ascending limb of the loop of Henle cells
Comparison
nNOS inhibitors in vivo; NO donor and 7-NI in… vs Control groups without nNOS inhibitors or basal…
Design
Preclinical
Authors
Loading...
May link NO-COX-2 signaling in rat renal responses to low salt; leaves open human translation for volume or RAS regulation.
Nitric oxide mediates the increased renal cortical COX-2 expression observed during volume depletion, suggesting an interaction between NO and COX-2 systems in regulating arteriolar tone and the renin-angiotensin system.
Cheng et al. (2000) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: