Population
188 plaque-purified type 3 poliovirus strains from 17 faecal specimens, derived from eight people
Design
Other
Follow-up
2 months
Authors
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Signals potential antigenic drift in polio infections; leaves open effects on vaccine efficacy and eradication strategies.
The study demonstrates rapid molecular and antigenic evolution of wild type 3 poliovirus during infection in individual hosts.
Kinnunen et al. (1990) studied this question.
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