Why the study?
Fibro-fatty infiltrations alter myocardial architecture and cause arrhythmias and sudden cardiac death, prompting the development of an MRI protocol to observe these modifications.
A novel 9.4 T 3D MRI protocol using IDEAL and MT sequences successfully identifies and quantifies fibro-fatty infiltrations in ex vivo human hearts, correlating with histology.
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May enable detailed fibro-fatty mapping ex vivo; leaves open in vivo validation before clinical use in ARVC.
Haliot et al. (2021) studied this question.
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