Why the study?
Does oral administration of various non-steroidal analgesics affect platelet aggregation in normal volunteers?
Population
Normal volunteers
Comparison
Oral administration of 10 non-steroidal analgesics vs Baseline (before intake)
Design
Other
Follow-up
Up to 5-8 days
Authors
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Aspirin uniquely prolongs platelet inhibition versus other analgesics in volunteers; leaves open translation to clinical bleeding or thrombotic outcomes.
Does oral administration of various non-steroidal analgesics affect platelet aggregation in normal volunteers?
Aspirin produces a uniquely long-lasting inhibition of the second wave of platelet aggregation compared to other non-steroidal analgesics.
Cronberg et al. (1984) studied this question.
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