Why the study?
Does intensive treatment with amlodipine/valsartan improve 24-h ambulatory blood pressure reductions compared to moderate treatment in hypertensive patients uncontrolled on ARB monotherapy?
Does intensive treatment with amlodipine/valsartan improve 24-h ambulatory blood pressure reductions compared to moderate treatment in hypertensive patients uncontrolled on ARB monotherapy?
Ambulatory blood pressure monitoring is more sensitive than clinic or home BP for detecting treatment differences between intensive and moderate amlodipine/valsartan dosing in uncontrolled hypertension.
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Intensive amlodipine/valsartan dosing yields greater 24-h BP control than moderate; extends ABPM utility for detecting titration differences in uncontrolled hypertension.
Giles et al. (2011) studied this question.
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