Why the study?
Is microalbuminuria associated with an altered renal hemodynamic response to captopril in lean patients with essential hypertension?
Population
106 lean patients with essential hypertension without detectable proteinuria
Comparison
Acute captopril challenge in patients with… vs Acute captopril challenge in normoalbuminuric…
Design
Cross-sectional
Authors
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Microalbuminuria may mark early intrarenal dysfunction in hypertension; leaves open whether captopril response testing improves risk stratification.
Is microalbuminuria associated with an altered renal hemodynamic response to captopril in lean patients with essential hypertension?
Microalbuminuria may serve as a marker of early functional or fixed intrarenal vascular dysfunction in never-treated lean patients with essential hypertension.
Mimran et al. (1994) studied this question.
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