Why the study?
Accurate assessment of tricuspid regurgitation severity and right ventricular function is crucial for guiding management in patients with this common condition.
Does CMR with 4D flow analysis improve the accuracy of tricuspid regurgitation assessment compared to TTE in patients with TR?
Does CMR with 4D flow analysis improve the accuracy of tricuspid regurgitation assessment compared to TTE in patients with TR?
CMR with 4D flow analysis provides valuable diagnostic information for quantifying tricuspid regurgitation, especially when TTE findings are discordant with clinical status.
4D flow CMR integration may refine TR grading in complex cases; leaves open prospective validation before wider adoption.
BACKGROUND: Tricuspid regurgitation (TR) is a common valvular heart disease associated with right ventricular dysfunction and an increased risk of hospitalization because of heart failure. Accurate assessment of TR severity and right ventricular function is crucial for guiding management. CASE SUMMARY: We present 3 cases of TR evaluated with transthoracic echocardiography (TTE) cardiac magnetic resonance (CMR) with integrated 4-dimensional (4D) flow analysis. Case 1 demonstrated torrential TR on CMR, underestimated by TTE. Case 2 showed concordant findings across modalities. Case 3 revealed a discrepancy, with CMR suggesting mild-to-moderate TR and TTE indicated severe TR. Management decisions were guided by clinical status and multimodal imaging. DISCUSSION: This series highlights the limitations of TTE in TR assessment and the utility of CMR with integrated 4D flow analysis for accurate TR quantification. TAKE-HOME MESSAGE: Integration of CMR with 4D flow analysis into the multimodal evaluation of TR provides valuable diagnostic information when TTE findings are discordant with clinical status or inadequate because of imaging constraints.
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Negm et al. (2025) studied this question.
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