Key result
The minor allele of rs4129218 on chromosome 12 showed a borderline protective association against left ventricular hypertrophy in a Korean population (adjusted OR 0.766).
Cross-Sectional (n=1,637)
Odds Ratio: 0.766 (95% CI 0.605–0.97)
p-value: p=0.027
The rs4129218 polymorphism on chromosome 12 showed a borderline association with lower left ventricular mass in a Korean population, consistent with previous findings in Caucasians.
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Borderline association in Koreans; extends Caucasian observations but leaves open causal role in LVH.
Park et al. (2015) conducted a cross-sectional in Left ventricular hypertrophy (n=1,637). rs4129218 minor allele (G) on chromosome 12 vs. Major allele homozygote (AA) was evaluated on Left ventricular hypertrophy (LVH) defined by LVM/BSA (OR 0.766, 95% CI 0.605-0.970, p=0.027). The minor allele of rs4129218 on chromosome 12 showed a borderline protective association against left ventricular hypertrophy in a Korean population (adjusted OR 0.766).
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