Why the study?
Does five doses of trivalent oral polio vaccine improve seroconversion rates in infants in the tropics compared to two or three doses?
Population
62 infants 1-12 months of age in the tropics
Comparison
Five doses of trivalent oral polio vaccine at… vs Two and three doses of trivalent oral polio…
Design
Cohort
Authors
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Five-dose OPV may boost seroconversion in tropical infants; leaves open optimal schedules pending RCTs.
Does five doses of trivalent oral polio vaccine improve seroconversion rates in infants in the tropics compared to two or three doses?
Administering five doses of oral polio vaccine to infants in the tropics achieves high seroconversion rates, overcoming factors like enterovirus interference and malnutrition.
Chopra et al. (1989) studied this question.
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