Why the study?
Does nebivolol and/or hydrochlorothiazide reduce clinic and ambulatory blood pressure in white patients with ambulatory hypertension?
Population
240 white patients with ambulatory hypertension (mean daytime ambulatory blood pressure of >= 90 mm Hg)
Comparison
Nebivolol, hydrochlorothiazide, or one of six… vs Placebo
Design
RCT, randomized, placebo-controlled
Follow-up
12 weeks
Authors
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Supports nebivolol-HCTZ combination for ambulatory hypertension; extends monotherapy data to dose-ranging regimens in white patients.
Does nebivolol and/or hydrochlorothiazide reduce clinic and ambulatory blood pressure in white patients with ambulatory hypertension?
Nebivolol, either as monotherapy or combined with low-dose hydrochlorothiazide, effectively reduces clinic and 24-hour ambulatory blood pressure in hypertensive patients.
Lacourcière et al. (1994) studied this question.
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