Key result
Prostacyclin and its pharmacological analogues are utilized for the treatment of pulmonary hypertension, right ventricular failure, and as an alternative to direct thrombin inhibitors in HIT.
Population
Patients with pulmonary hypertension, right ventricular failure, or type II heparin-induced thrombocytopenia…
Design
Review
Authors
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Supports current applications in PH, RV failure, and HIT; leaves open need for randomized validation.
This review highlights the pharmacological properties of prostacyclins and their clinical utility in managing pulmonary hypertension, right heart failure, and heparin-induced thrombocytopenia during cardiac surgery.
Deshpande et al. (2017) conducted a review in Pulmonary hypertension, right heart failure, and heparin-induced thrombocytopenia in cardiac surgery. Prostacyclin (PGI 2) and its derivatives was evaluated. Prostacyclin and its pharmacological analogues are utilized for the treatment of pulmonary hypertension, right ventricular failure, and as an alternative to direct thrombin inhibitors in HIT.
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